Suppression of the Intrinsic Apoptosis Pathway by Synaptic Activity
نویسندگان
چکیده
منابع مشابه
Suppression of the intrinsic apoptosis pathway by synaptic activity.
Synaptic activity promotes resistance to diverse apoptotic insults, the mechanism behind which is incompletely understood. We show here that a coordinated downregulation of core components of the intrinsic apoptosis pathway by neuronal activity forms a key part of the underlying mechanism. Activity-dependent protection against apoptotic insults is associated with inhibition of cytochrome c rele...
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ژورنال
عنوان ژورنال: Journal of Neuroscience
سال: 2010
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.5115-09.2010